Table 2.
Effect of AC3 knockout on cell death related signaling pathways.
| Pathway Name | Hits | Total | p-Value | Percent |
|---|---|---|---|---|
| Apoptotic DNA fragmentation and tissue homeostasis | 1 | 9 | 0.000 | 11.1% |
| Apoptotic Signaling in Response to DNA Damage | 3 | 21 | 0.0 | 14.2% |
| Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia | 3 | 23 | 0.0 | 13% |
| Erk1Erk2 Mapk Signaling pathway | 4 | 28 | 0.9 | 14.2% |
| Erythropoietin mediated neuroprotection through NF-kB | 3 | 11 | 0.0324 | 27.3% |
| FAS signaling pathway (CD95) | 3 | 28 | 0.037 | 10.7% |
| MAPKinase Signaling Pathway | 5 | 77 | 0.0004 | 6% |
| p38 MAPK Signaling Pathway | 4 | 31 | 0.0001 | 13% |
| p53 Signaling Pathway | 4 | 16 | 0.0 | 25% |
| Th1/Th2 Differentiation | 7 | 18 | 0.0 | 39% |
| WNT Signaling Pathway | 2 | 25 | 0.0 | 8% |
Hit represents the numbers of differentially expressed genes identified by microarray hybridization on the given term. Total represents the total gene numbers on the given term. Percent means the % of hit to total.