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. 2015 Dec 4;16(12):28931–28942. doi: 10.3390/ijms161226145

Figure 4.

Figure 4

The LPS-induced protein penetration and lung injury are greater in TDAG8-deficeient mice than in WT mice. (A) BAL fluid samples were collected at the indicated time after PBS or LPS instillation for measurement of protein concentration. Data are mean ± SEM of n = 12–17 for each group. The effect of TDAG8 deficiency is significant, * p < 0.05 (TDAG8TP/TP-LPS vs. WT-LPS); (B) Proteins of BAL fluid sample (duplicate for each group) were separated by SDS-PAGE and stained with Coomassie brilliant blue. Mouse serum at two different concentrations (right two lanes) was used as standard; (C) Histological analysis of lung sections was performed 4 h after PBS or LPS instillation. Three representative lung sections per mouse, from 5–10 mice, are shown for each group. Scale bar is 100 µm; (D) Lung injury scores by analysis of histopathological sections from lungs 4 h after PBS or LPS instillation. Data are mean ± SEM of n = 5–10 for each group. The effect of TDAG8 deficiency is significant, * p < 0.05 (TDAG8TP/TP-LPS vs. WT-LPS).