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Mast cell-associated disease-specific pain syndromes, mast cell activation and its common activators: ATP (Adenosine tri-phosphate), chemokines, C3α, C5α (Complement 3α, 5α), estrogens, immunoglobins (IgE, IgG1), CGRP (calcitonin gene-related peptides), SP (substance P), CRH (corticotropin-releasing hormone), NGF (nerve growth factor), SCF (stem cell growth factor), trypsin, tryptase, venoms, vasoactive intestinal peptides.
