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Pharmacokinetic parameters of plasma CLZ concentration after intravenous injection of CLZ solution and CLZnano dispersion.
| A (μg/mL) | A (/min) | B (μg/mL) | β (×10−2, /min) | AUCCLZ (μg·min/mL) | MRTCLZ (min) | |
|---|---|---|---|---|---|---|
| CLZ solution | 3.87 ± 0.27 | 0.16 ± 0.01 | 1.27 ± 0.12 | 3.41 ± 0.52 | 60.0 ± 6.9 | 21.6 ± 1.7 |
| CLZnano dispersion | 3.85 ± 0.41 | 0.17 ± 0.01 | 1.31 ± 0.10 | 3.08 ± 0.24 | 57.1 ± 8.1 | 24.1 ± 2.7 |
