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. 2015 Dec 9;16(12):29370–29382. doi: 10.3390/ijms161226174

Figure 3.

Figure 3

Blocking ICAM-1 and VCAM-1 in HCT-116 cells inhibits their adhesion to HUVECs. HCT-116 cells were pretreated with specific neutralizing antibodies (A) or siRNAs (B) for control (IgG/si-CL), ICAM-1, VCAM-1, or both and then were maintained as control or stimulated with resistin. HCT-116 cell adhesion was determined. Data represent the mean ± SEM from four independent experiments. * p < 0.05 vs. control cells (CL); # p < 0.05 vs. cells pretreated with IgG or si-CL and then treated with resistin only; ** p < 0.05 vs. cells pretreated with ICAM-1 or VCAM-1 neutralizing antibody and then treated with resistin.