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. 2015 Dec 11;16(12):29682–29716. doi: 10.3390/ijms161226191

Scheme 5.

Scheme 5

Kinetic enzymatic hydrolysis of racemic methyl-1,4-benzodioxan-2-carboxylate, affording intermediates used in the synthesis of (S)-Prosimpal, (S)-Piperoxan, (S,S)-Dibozane and (S)-Doxazosin [15].