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. 2015 Dec 15;16(12):29815–29828. doi: 10.3390/ijms161226203

Figure 3.

Figure 3

Figure 3

Figure 3

Genomic copy number alteration and expression of AURKA, SAMD4, and miR-25 in TCGA human clinical cancer samples across a variety of cancer types. (A) Genomic copy number amplification of AURKA in human clinical cancer samples; (B) Up-regulation of AURKA expression in human stomach cancer samples, showing its gain and amplification; (C) Genomic copy number deletion of SAMD4 in human clinical cancer samples; (D) Down-regulation of SAMD4 expression in human stomach cancer samples, showing its deletion; (E) Binding of miR-25 to TOB1 mRNA 3′-UTR; (F) Genomic copy number amplification of miR-25 in human clinical cancer samples; and (G) Up-regulation of miR-25 expression in human stomach cancer samples, showing its gain and amplification.