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. 2015 Dec 16;16(12):29900–29910. doi: 10.3390/ijms161226211

Figure 3.

Figure 3

Expression of retinal angiogenesis-related proteins in OIR mice. Pro- and anti-angiogenic factor expression in the retina was analyzed using protein arrays and quantified using ImageJ software. The negative control is located in the lower right corner of the arrays, and the positive controls are located in other three corners. The proteins for which expression was modulated in GBT-treated retinas are indicated by numbers. Con, normal control mice; OIR, saline-treated OIR mice; GBT-50, OIR mice treated with 50 mg/kg GBT; and GBT-100, OIR mice treated with 100 mg/kg GBT. 1: FGF2, fibroblast growth factor 2; 2: IGFBP-1, insulin-like growth factor binding protein 1; 3: MCP-1, Monocyte Chemoattractant Protein-1; 4: CXCL4, chemokine (C-X-C motif) ligand 4; 5: PAI-1, Plasminogen activator inhibitor-1. Data are represented as mean ± SE (n = 4). # p < 0.0001 for control group vs. OIR group; * p < 0.05 for OIR group vs. GBT-treated group.