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Correlation of learning spatial discrimination in the three chamber task and whole brain DOPAC levels (pg/g tissue). There was a significant ( p < 0.001) increase in accuracy on the simple spatial discrimination in the three-chamber task associated with increases in whole brain concentrations of the dopamine metabolite DOPAC (Eddins et al., 2009 ). The nicotine exposure concentration was 100 mg/l for 3 min immersion ending 20 min before testing. Sacrifice occurred just after testing.
