Table 5.
Clusters with a significant positive relation between right and left dlPFC RSFC and years since age 10 of substance use onset.
| Voxels | Peak (x, y, z) | Region | BA |
|---|---|---|---|
| Right dlPFC | |||
| 172 | 16, 42, 28 | Right medial prefrontal cortex, anterior cingulate | 9 |
| 157 | 0, 58, −16 | Ventromedial prefrontal cortex | 11 |
| 111 | 36, 14, 50 | Right dorsolateral prefrontal cortex | 8 |
| 81 | 8, 54, 34 | Right dorsomedial prefrontal cortex | 9 |
| 69 | 20, −104, −5 | Right lingual gyrus | 18 |
| 57 | −44, 48, −12 | Left ventrolateral prefrontal cortex | 11 |
| Left dlPFC | |||
| 160 | 16, 40, 28 | Right anterior cingulate | 9 |
dlPFC = dorsolateral prefrontal cortex; PFC = prefrontal cortex; ACC = anterior cingrulate cortex; RSFC = resting state functional connectivity; Peak (x, y, z) = MNI coordinates for the voxel with the highest coefficient within each cluster; BA = Brodmann's area; Voxel-wise threshold: t = 3.433, p = 0.001 for minimum cluster size of 45 voxels, alpha <0.01.