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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Nutr Biochem. 2015 Aug 20;27:16–26. doi: 10.1016/j.jnutbio.2015.08.012

Figure 9. Gln dose-dependently attenuates ethanol-induced liver injury.

Figure 9

Mice were fed a Gln-free amino acid diet with (Ethanol fed) or without (Pair fed) ethanol (1–6% over 4 weeks) and without (GF) or with 8.4 g/L (GN) or 16.8 g/L (GS) Gln supplementation. Liver weights (A) were recorded, plasma ALT levels measured (B) and H & E stained paraffin sections of liver were imaged by light microscopy (C). Cryosections of liver were stained with Oil Red-O and imaged by light microscopy (D), and liver extracts were assayed for triglyceride content. Values are mean ± SE (n = 6). Asterisks indicate the values that are significantly (p<0.05) different from values for corresponding non-ethanol pair fed group, and the hash tags indicate the values that are significantly (p<0.05) different from corresponding values for “GF” group.