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. 2015 Dec 13;2015:163591. doi: 10.1155/2015/163591

Figure 2.

Figure 2

PCB 102-induced cell proliferation is mediated by ERα. MCF-7/BOS cells were treated with 1 nM E2 or 5 μM PCB 102 with and without the ERα-specific inhibitor MPP (1 μM) or the ERβ-specific inhibitor PHTPP (1 μM) for 72 hours. Cell numbers were determined by hemocytometer and expressed as a percentage of the DMSO control (set at 100%). Values are expressed as mean ± SE (n = 3). ∗Significantly different compared to control, P < 0.05; ǂsignificantly different compared to E2 treatment, P < 0.05; and #significantly different compared to PCB treatment, P < 0.05.