Table 5.
Resting levels of serum thiobarbituric acid reactive substances (TBARSs), xanthine oxidase (XO), total antioxidant capacity (T-AOC), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-PX), total glutathione (T-GSH), oxidized glutathione (GSSG), reduced glutathione (GSH), GSH/GSSG ratio, and uric acid (UA) of altitude (Alt) and sea-level (SL) runners before (pre) and after (post) the 12-week off-season conditioning program.
| Alt (n = 13) | SL (n = 13) | |||
|---|---|---|---|---|
| Before | After | Before | After | |
| TBARS (nmol·mL−1) | 4.81 ± 1.15 | 4.46 ± 1.22 | 2.62 ± 1.02a | 2.17 ± 0.80a |
| XOD (U·L−1) | 20.8 ± 4.2 | 15.9 ± 4.9∗ | 18.2 ± 6.5 | 12.4 ± 3.4∗ |
| T-AOC (U·mL−1) | 14.6 ± 3.2 | 14.5 ± 7.2 | 14.1 ± 2.8 | 12.4 ± 3.8 |
| SOD (U·mL−1) | 55.6 ± 18.6 | 55.6 ± 13.6 | 77.7 ± 23.0a | 67.8 ± 21.6 |
| CAT (U·mL−1) | 1.48 ± 0.50 | 2.16 ± 0.60∗ | 1.46 ± 0.60 | 1.63 ± 0.67a† |
| GSH-PX (U·mL−1) | 114.5 ± 24.1 | 88.1 ± 32.8∗ | 89.8 ± 21.4a | 73.1 ± 38.2 |
| T-GSH (μmol·L−1) | 17.5 ± 1.1 | 18.5 ± 2.4 | 18.2 ± 1.3 | 17.1 ± 1.2∗† |
| GSSG (μmol·L−1) | 5.31 ± 0.75 | 6.41 ± 0.93∗ | 5.96 ± 0.46a | 7.01 ± 0.87∗ |
| GSH (μmol·L−1) | 6.88 ± 1.60 | 5.65 ± 1.29∗ | 6.31 ± 1.31 | 3.11 ± 1.50∗a† |
| GSH/GSSG | 1.37 ± 0.62 | 0.89 ± 0.21∗ | 1.07 ± 0.26 | 0.47 ± 0.28∗a† |
| UA (mg·L−1) | 34.3 ± 9.0 | 38.1 ± 7.5∗ | 31.3 ± 5.5 | 28.1 ± 5.2∗a† |
Values are mean ± SD.
∗Significantly different from corresponding preconditioning value, P < 0.05.
aSignificantly different from corresponding Alt value, P < 0.05.
†Conditioning-induced change is significantly different from corresponding Alt value, P < 0.05.