Table 4.

Results of multilevel models using weekly moderate/severe anticholinergic medication use to predict outcomes

	Clox 1		Barthel		Orientation		Digit Forward		Digit Backward		Memory		Delirium severity		Length of stay
Predictor	b	SE	b	SE	b	SE	b	SE	b	SE	b	SE	b	SE	b	SE
Any AC	0.502	0.508	−5.761	1.994	−0.195	0.203	0.235	0.426	−0.575	0.259	−0.008	0.144	0.160	0.170	0.227	0.109
Gender (ref = female)	−1.853	0.961	2.037	4.983	−0.006	0.463	0.092	0.753	0.001	0.548	−0.360	0.247	−0.274	0.134	−0.139	0.102
Ethnicity (ref = Caucasian)	−1.771	2.835	31.554	15.404	1.479	1.418	1.385	2.251	−0.656	1.613	1.149	0.733	−0.586	0.451	−0.277	0.337
Charlson	0.122	0.215	2.334	1.152	0.053	0.106	0.019	0.168	−0.001	0.121	0.001	0.055	−0.070	0.031	0.020	0.024
CDR	−3.086	0.755	−3.655	3.798	−1.225	0.357	−1.309	0.567	−1.207	0.414	−0.617	0.187	0.600	0.108	0.021	0.079
Age	−0.036	0.077	−1.051	0.363	−0.035	0.034	0.136	0.059	0.050	0.045	−0.041	0.020	−0.025	0.011	0.016	0.008
APOE (ref = present)	0.270	1.018	1.194	5.043	−0.003	0.472	−1.389	0.761	−0.656	0.545	0.233	0.248	−0.322	0.332	0.090	0.105
APOE*AC	−0.238	0.998	2.235	3.942	0.298	0.400	−0.643	0.836	0.762	0.507	0.333	0.282	−0.050	0.345	--	--
Repetition	−0.001	0.010	0.113	0.035	0.006	0.004	0.004	0.008	0.009	0.005	0.007	0.003	0.000	0.006	--	--
Education	1.706	1.571	22.438	8.405	0.842	0.773	−1.493	1.225	−0.728	0.880	0.391	0.398	−0.013	0.231	−0.001	0.176
Previous week's performance	0.353	0.080	0.318	0.063	0.123	0.058	0.270	0.062	0.168	0.064	0.427	0.061	1.155	0.079	--	--
Days WP	−0.220	0.161	−0.121	0.530	0.045	0.060	−0.102	0.130	0.026	0.078	0.027	0.044	0.299	0.089	--	--

Note. AC = anticholinergic; Bold values p < .05; b = unstandardized regression weight; t-test (df_between = 90, df_within = 1099)