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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Oral Oncol. 2015 Nov 14;52:97–103. doi: 10.1016/j.oraloncology.2015.10.016

Table 2.

Patterns and distribution of recurrence in early vs. late survivors

Early
survivors
n=20;
N (%)
Late
survivors
n=81;
N (%)
HPV-negative (N=26) HPV-positive (N=75)

P-
value
Early Late P-
value
Early Late P-
value

Site of recurrence:
Locoregional 9 (45) 53 (65.4) .093 4 (44.4) 11(64.7) .32 5 (45.5) 42(65.6) .201
Distant 11 (55) 28 (34.6) 5 (55.6) 6 (35.3) 6 (54.5) 22(34.4)

Number of recurrent episodes: .087* .13 .33*
Single 14 (70) 40 (49.4) .23^ 7 (77.8) 8 (47.1) 7 (63.6) 32 (50) .59^
Multiple 5 (25) 37 (45.7) 2 (22.2) 9 (52.9) 3 (27.3) 28(43.8)
Unknown 1 (5) 4 (4.9) 0 (0) 0(0) 1 (9.1) 4 (6.2)

Time to Recurrence: <.001 .019 <.001
< 12 months 15 (75) 16 (19.8) 8 (88.9) 7 (41.2) 7 (63.6) 9 (14.1)
>= 12 months 5 (25) 65 (80.2) 1 (11.1) 10(58.8) 4 (36.4) 55(85.9)
*

statistic excluding unknowns

^

statistic including unknowns