Table 1.
Cell cycle associated genes upregulated by Nr4a1 and Nr4a3 but not Nkx6.1. Genes upregulated by Nr4a1 and Nr4a3 that are not regulated by Nkx6.1 were selected based on changes greater than 1.5-fold and p values less than 0.05. Genes were defined by the GO category cell cycle.
| Gene name | Fold change | p value | Process |
|---|---|---|---|
| Gas2 | 12.27 | 0.001577852 | Cytokinesis |
| Tgfa | 2.4 | 0.000103799 | Growth factor |
| Rapgef5 | 2.31 | 0.004103808 | Ras activator |
| Nuf2 | 2.24 | 0.002117132 | Centromere |
| Chl1 | 2.17 | 0.023016307 | G2/M transition |
| Top2a | 2.04 | 0.002104745 | DNA replication |
| Cks2 | 1.92 | 0.007478331 | CDK regulation |
| Gins4 | 1.87 | 0.003569736 | DNA replication |
| Aspm | 1.83 | 0.004862977 | Spindle formation |
| Cdk5r1 | 1.78 | 0.00289215 | CDK regulation |
| Prc1 | 1.75 | 0.005448853 | Cytokinesis |
| Kif2c | 1.75 | 0.000350709 | Centromere |
| Dscc1 | 1.73 | 0.008438809 | DNA replication |
| Kif15 | 1.66 | 0.008896449 | Microtubules |
| Ncapd2 | 1.65 | 0.004007301 | DNA condensation |
| Prim1 | 1.58 | 0.001821116 | DNA replication |