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. Author manuscript; available in PMC: 2015 Dec 28.
Published in final edited form as: J Am Chem Soc. 2015 Aug 7;137(32):10096–10099. doi: 10.1021/jacs.5b05765

Figure 1.

Figure 1

(a) The prospect of replacing missing protein channels with small molecule mimics. (b) Chemical structures of the archetypical ion channel-forming small molecule amphotericin B 7 and its single atom-deficient and channel-inactivated derivative C35-deoxy amphotericin B (C35deOAmB).