Table 3.
Ceramide profiles of mice following a standard diet or HFD fed mice for 14 weeks.
| Ceramide | ST/S | ST/ET | ST/RT | HFD/S | HFD/ET | HFD/RT |
|---|---|---|---|---|---|---|
| (μmol/L) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
| d18:1/16:0 | 0.253 (0.027) | 0.228 (0.020) | 0.255 (0.044) | 0.749 (0.182)a | 0.723 (0.097)a | 0.659 (0.119)a |
| d18:1/18:0 | 0.039 (0.027) | 0.051 (0.029) | 0.057 (0.027) | 0.192 (0.096)a | 0.201 (0.058)a | 0.174 (0.059)a |
| d18:1/20:0 | 0.079 (0.004) | 0.062 (0.026) | 0.073 (0.019) | 0.483 (0.202)a | 0.398 (0.113)a | 0.439 (0.145)a |
| d18:1/22:0 | 0.677 (0.089) | 0.477 (0.118) | 0.576 (0.103) | 2.672 (1.120)a | 2.060 (0.286) | 2.404 (1.001)a |
| d18:1/23:0 | 0.350 (0.046) | 0.373 (0.070) | 0.397 (0.033) | 0.627 (0.149)a | 0.462 (0.052)∗ | 0.521 (0.095) |
| d18:1/24:1 | 1.722 (0.065) | 1.261 (0.097) | 1.323 (0.108) | 2.782 (0.939) | 1.815 (0.376)∗ | 1.819 (0.284)∗ |
| d18:1/24:0 | 1.027 (0.185) | 0.819 (0.119) | 0.949 (0.142) | 1.035 (0.163) | 0.814 (0.083) | 0.950 (0.155) |
| HexCer d18:1/16:0 | 0.274 (0.062) | 0.239 (0.030) | 0.252 (0.019) | 0.860 (0.197)a | 0.791 (0.142)a | 0.725 (0.093)a |
| HexCer d18:1/24:1 | 0.815 (0.126) | 0.698 (0.063) | 0.806 (0.082) | 1.466 (0.307)a | 1.398 (0.223)a | 1.092 (0.155)∗ |
ST: standard diet, HFD: high fat diet, S: sedentary, ET: endurance training, and RT: resistance training. SD: standard deviation. For each group n = 5. aST fed groups versus corresponding HFD groups (p < 0.005), ∗comparison within ST groups or HFD groups, sedentary versus ET or RT (p < 0.005): HexCer: hexosylceramide.