Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 14;2016:1689602. doi: 10.1155/2016/1689602

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Liming Yu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Effects of BBR and SIRT1 siRNA on oxidative stress and inflammation response in SIR-injured cardiomyocyte. H9C2 cardiomyocytes were exposed to control siRNA or SIRT1 siRNA and then treated with BBR (50 μmol/L for 8 hr). Next, cells were subjected to simulated ischemia/reperfusion (SIR, 2 hr/4 hr) treatment. Then, oxidative stress level was measured. (a) Cardiomyocyte superoxide generation. (b) gp91^phox expression. Top images: representative blots. (c) Cell supernatants IL-6 level. (d) Cell supernatants TNF-α level. The results are expressed as the mean ± SEM, n = 8/group. ^&& P < 0.01 versus control siRNA group, ^@@ P < 0.01 versus SIR + control siRNA group, and ^%% P < 0.01 versus SIR + BBR + control siRNA group.