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Cystic colonies generated from Sox9-tagged cells. A: Embryonic Sox9+ progenitors in the pancreas capable of generating cystic colonies; a: Sox9 is expressed in most ductal progenitors in E11.5 mouse pancreas; b: Cystic colonies are formed from purified Sox9-eGFP+ progenitors in E11.5 mouse pancreas; B: Purified Sox9+ cells in adult mouse pancreas capable of generating cystic colonies under a phase contrast (a) or a fluorescence microscope (b). Adapted and modified from[20,21].
