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Modulation of secreted frizzled-related protein-stimulated induction of CXCL8 mRNA. sFRP1/2-stimulated CXCL8 mRNA expression is suppressed in the presence of the PLC inhibitor U73122 suggesting that signaling is via the Wnt/calcium non-canonical pathway (values are mean ± SD). aP < 0.05 vs HMSCGM-treated levels. sFRP1/2: Secreted frizzled-related protein 1/2; PLC: Phospholipase C.
