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(a) Electropherogram of 5’-3’ strand of the exon 10 of FSHR gene, showing a wild type sequences (upper panel) of a control subject and heterozygous mutant sequence (lower panel) resulting in change of nucleotide ‘C’ to ‘A/C’ (1346 position) leading to Thr449Asn substitution identified in patient who developed spontaneous ovarian hyperstimulation syndrome during pregnancy. (b) Schematic representation of FSHR showing the position of naturally occurring novel mutationThr449Asn
