Table 2.
Genetic Impact on Cognitive Performance
| Cognitive Test | TT vs MMe | t | p | Df | N (MM, TT) | Effect size |
|---|---|---|---|---|---|---|
| RBANS coding a | −7.270 | −2.289 | 0.026* | 48 | 54 (27, 27) | −0.513 |
| Trails A a | 2.745 | 0.663 | 0.511 | 47 | 53 (26, 27) | 0.153 |
| RBANS digit span a | −0.152 | −0.189 | 0.851 | 48 | 54 (27, 27) | −0.043 |
| CWIT Trial 1 b, c | 0.280 | 0.176 | 0.861 | 46 | 52 (27, 25) | 0.049 |
| CWIT Trial 2 b | −0.339 | −0.215 | 0.831 | 47 | 53 (27, 26) | −0.049 |
| RBANS picture naming a,d | −0.205 | −0.847 | 0.401 | 48 | 54 (27, 27) | −0.193 |
| RBANS semantic fluency a | −3.797 | −2.416 | 0.019* | 48 | 54 (27, 27) | −0.541 |
| Word generation FASa | −2.309 | −1.278 | 0.209 | 36 | 42 (18, 24) | −0.349 |
| Word generation | −3.713 | −2.284 | 0.028* | 36 | 42 (18, 24) | −0.614 |
| Trails B b | 24.495 | 1.236 | 0.222 | 48 | 54 (27, 27) | 0.281 |
| LNSa | −0.688 | −0.842 | 0.404 | 48 | 54 (27, 27) | −0.192 |
| CWIT Trial 3 b | 1.033 | 0.181 | 0.858 | 47 | 53 (27, 26) | 0.041 |
| CWIT Trial 4 b | −4.476 | −0.643 | 0.523 | 47 | 53 (27, 26) | −0.147 |
| Maze task b | 94.365 | 1.429 | 0.162 | 36 | 42 (18, 24) | 0.389 |
Note: No significant differences were observed between TT or MM participants with and without imaging data on any of the cognitive measures (all p’s > .05)
a
Number Correct,
b
Completion Time,
c
One TT participant was removed from the analysis due to its Cook’s distance larger than 1,
d
Logistic regression showed the same and statistically non-significant trend as the linear regression.
*
Statistically Significant p < .05