Table 4. Multivariable associations between CVH score and incident HF.
Model | HR (95% CI) | p-value |
---|---|---|
1. Adjusted for age and sex | 0.77 (0.72, 0.83) | <0.0001 |
2. Adjusted for age, sex and LVM | 0.82 (0.74, 0.90) | <0.0001 |
3. Adjusted for age, sex and interim MI | 0.80 (0.74, 0.86) | <0.0001 |
4. Adjusted for age, sex, LVM and interim MI | 0.84 (0.76, 0.93) | 0.0006 |
5. Adjusted for age, sex, LVM, interim MI, log (BNP) and UACR* | 0.83 (0.75, 0.93) | 0.0008 |
HR indicates hazard ratio; BNP, B-type natriuretic peptide; LVM, left ventricular mass; MI, myocardial infarction; UACR, urine albumin-to-creatinine ratio.
Values represent HRs for each 1-point higher CVH score.
Due to unavailability of biomarker measurements in a number of participants, the sample size for this model included 2046 participants. When tested in this smaller sample, the results for the other models were unchanged.