Table 3.
Changes in Baseline Characteristics from 1990-2000 to 2001-2010 by Heart Failure Status at Follow-up
| Characteristic | Overall (n=2596) |
HF Status at Follow-up |
||||
|---|---|---|---|---|---|---|
| Developed HF (n=902) |
Did not Develop HF (n=1694) |
|||||
| 1990-2000 (n=1211) |
2001-2010 (n=1385) |
1990-2000 (n=541) |
2001-2010 (n=361) |
1990-2000 (n=670) |
2001-2010 (n=1024) |
|
| Age, years | 67.0 (14.2) * | 66.2 (14.8) * | 72.2 (12.6) * | 74.2 (13.0) * | 62.7 (14.0) * | 63.3 (14.3) * |
| Male | 689 (57) | 877 (63) | 255 (47) | 183 (51) | 434 (65) | 694 (68) |
| BMI, kg/m2 | 27.9 (5.7) * | 28.9 (6.0) * | 28.2 (6.0) * | 28.5 (6.3) * | 27.7 (5.5) * | 29.0 (5.9) * |
| Hypertension | 657 (54) | 914 (66) | 357 (66) | 288 (80) | 300 (45) | 626 (61) |
| Hyperlipidemia | 468 (39) | 883 (64) | 210 (39) | 235 (65) | 258 (39) | 648 (63) |
| Current smoking | 350 (29) | 320 (23) | 128 (24) | 78 (22) | 222 (33) | 242 (24) |
| Diabetes mellitus | 229 (19) | 305 (22) | 138 (26) | 111 (31) | 91 (14) | 194 (19) |
| Charlson comorbidity index | 1 (0, 2) † | 1 (0, 2) † | 1 (0, 2) † | 2 (1, 4) † | 0 (0, 1) † | 1 (0, 2) † |
| Killip >1 | 349 (29) | 297 (22) | 228 (43) | 173 (49) | 121 (18) | 124 (12) |
| ST-elevation MI | 458 (39) | 366 (27) | 188 (36) | 90 (25) | 270 (42) | 276 (27) |
| Anterior MI | 444 (38) | 463 (34) | 218 (41) | 161 (45) | 226 (35) | 302 (30) |
| Q-wave MI | 638 (56) | 667 (52) | 306 (60) | 212 (63) | 332 (53) | 455 (48) |
| PCI | 530 (44) | 872 (63) | 200 (37) | 176 (49) | 330 (49) | 696 (68) |
| CABG | 124 (10) | 115 (8) | 63 (12) | 43 (12) | 61 (9) | 72 (7) |
| Atrial fibrillation | 145 (12) | 135 (10) | 95 (18) | 68 (19) | 50 (8) | 67 (7) |
| Estimated GFR, <60 mL/min per 1.73 m2 |
627 (52) | 576 (42) | 339 (63) | 220 (61) | 288 (44) | 356 (35) |
| HF Characteristics | ||||||
| HFrEF | — | — | 363 (67) | 200 (55) | — | — |
| Time from index MI, days ‡ | — | — | 2 (0, 64) † | 2 (0, 65) † | — | — |
BMI = body mass index; CABG = coronary artery bypass graft surgery; GFR = glomerular filtration rate; HF = heart failure; HFrEF = heart failure with reduced ejection fraction; MI = myocardial infarction; PCI = percutaneous coronary intervention; SD = standard deviation.
Values expressed as n (% of non-missing values) unless otherwise noted.
*
Value expressed as mean (SD).
†
Value expressed as median (25th, 75th percentiles).
‡
Follow-up restricted to 5 years after MI (385 patients developed HF from 1990-2000; 342 patients developed HF from 2001-2010).