Skip to main content
. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Immunity. 2015 Dec 15;43(6):1053–1063. doi: 10.1016/j.immuni.2015.11.007

Figure 2. Angle of approach to the Env trimer by PGT121 family members as determined by EM.

Figure 2

Schematic representation of Abs from the PGT121 phylogenetic tree (Sok et al., 2013) (displayed horizontally) in complex with SOSIP trimer as determined from negative-stain EM reconstructions for Ab:SOSIP complexes. The correlation values were calculated by fitting the EM reconstruction of the 3H+3L:SOSIP.664-N137A complex into the corresponding reconstructions of the 32H+3L:SOSIP.664, PGT124:SOSIP.664, 9H+109L:SOSIP.664 and PGT122:SOSIP.664 complexes (please see Figure S2).

HHS Vulnerability Disclosure