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. 2015 Dec 22;11(12):e1004674. doi: 10.1371/journal.pcbi.1004674

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© 2015 Veliz-Cuba et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 14 — The parameter values at cell division are sampled from the same normal distribution regardless of the value of the parameters in the mother cell. A. Compared to the case of lineage dependence (Fig 6 in main text), the amplitude variability is lower and hence a higher level of parameter variability is needed to match the amplitude variability seen in experimental data. B. The amplitude correlation in simulations can match the experimental data by appropriately tuning the noise parameters Ω and Γ. C. The set of parameters obtained from panels A and B do not overlap, and it is not possible to match simultaneously the amplitude variability and correlation seen in experimental data.