Table 1. Screening of plant extracts for anti-DENV activity.
No. | Name of Plant | Part used a | Antiviral Activity b |
---|---|---|---|
1 | Aconitum heterophyllum | Rhizome | - |
2 | Andrographis paniculata | Whole plant | - |
3 | Azadirachta indica | Bark | - |
4 | Cedrus deodara | Resin | - |
5 | Cissampelos pareira | Aerial part | + |
6 | Coptis teeta | Root | + |
7 | Cyperus rotundus | Rhizome | - |
8 | Desmodium gangeticum | Whole plant | + |
9 | Enicostemma littorale | Whole plant | - |
10 | Fumaria indica | Whole plant | + |
11 | Ocimum sanctum | Whole plant | - |
12 | Phyllanthus amarus | Whole plant | + |
13 | Picrorhiza kurroa | Rhizome | ± |
14 | Premna mucronata | Bark | + |
15 | Swertia chirayata | Whole plant | - |
16 | Terminalia chebula | Fruit | + |
17 | Tinospora cordifolia | Stem | + |
18 | Aloe vera | Leaf | - |
19 | Citrullus colocynthis | Root | - |
aMethanolic extracts were prepared using parts of the plant mentioned in Ayurvedic literature
bAntiviral activity against DENV-3 screened using Type-1 assay. “+” indicates active extract (IC50 <25μg/ml); “±” indicates borderline extracts (IC50 = ~25μg/ml); “-” indicates inactive extract (IC50 >25μg/ml)