Table 2. Extracts with Pan-DENV inhibitory activity.
| No. | Extract | Antiviral activity (IC50, μg/ml) | ||||
|---|---|---|---|---|---|---|
| DENV-1 a | DENV-2 a | DENV-3 a | DENV-4 a | DENV-3 b | ||
| 1 | Cissampelos pareira | 11.11 | 1.97 | 3.17 | 1.23 | 78 |
| 2 | Coptis teeta | 11.11 | 5.04 | 7.87 | 33.33 | >200 |
| 3 | Desmodium gangeticum | 12.5 | 6.7 | 14.62 | 12.5 | >200 |
| 4 | Fumaria indica | 12.5 | 7.02 | 11.32 | 12.5 | >200 |
| 5 | Phyllanthus amarus | 3.7 | 8.33 | 20.76 | 11.11 | 145 |
| 6 | Picrorhiza kurroa | 12.5 | 16.02 | 27.14 | 25 | >200 |
| 7 | Premna mucronata | 12.5 | 27.9 | 21.37 | 12.5 | >200 |
| 8 | Terminalia chebula | 25 | 70 | 11.2 | 50 | >100 |
| 9 | Tinospora cordifolia | 50 | 58.75 | 16.02 | 25 | >100 |
aType-1 assay (carried out using all DENV serotypes)
bType-2 assay (carried out using DENV-3 alone)