Table 1. A summary of all parameters and values used in the models.

Parameter	Description	Value	Ref.
λ	CD4+ T cell generation rate	/	Fitted
k	Viral infection rate	/	Fitted
d 1	Death rate of uninfected CD4+ T cells	0.01 day -1	[31]
γ i	Effectiveness of cytokines on infection	/	Fitted
d 2	Death rate of infected CD4+ T cells	1 day -1	[36]
f	Fraction of abortive infection	0.95	[23]
d 3	Death rate of abortively infected cells	0.001 day -1	[31]
p v	Viral production rate	/	Fitted
d 4	Viral clearance rate	23 day -1	[31]
N c	Burst size of cytokines	15 molecule	/
d 5	Decay rate of cytokines	6.6 day -1	[38]
λ 1	Generation rate of CD4+ in blood	/	Fitted
λ 2	Generation rate of CD4+ in lymph node	5×105 cell ml -1 day -1	See text
σ 1	CD4+ transfer rate to lymph node	0.01 day -1	See text
σ 2	CD4+ transfer rate to blood	0.0002 day -1	See text
γ r	Effect of cytokines on CD4+ transportation	/	Fitted
D 1	Rate of viral transfer to blood	0.1 day -1	/
D 2	Rate of viral transfer to lymph node	0.2 day -1	/
p v1	Viral production rate in blood	/	Fitted
p v2	Viral production rate in lymph node	2000 day -1	[32]
ρ	Hill coefficient in exponential function	2×10−4 ml molecule -1	/
α	Killing rate of CD8+ T cells	0.01 ml cell -1 day -1	/
p E	Max activation rate of CD8+ T cells	100 cells ml -1 day -1	/
θ	Half max saturation of CD8+ activation	50 cells ml -1	/
η	Effect of CD4+ T cells on CD8 activation	500 cells/μl	/
d E	Death rate of CD8+ T cells	0.06 day -1	[62]
μ	Fraction of latent infection	0.001	[32]
p L	Proliferation of latently infected T cells	0.001 day -1	See text
φ	Effect of cytokines on latent proliferation	10−2 ml molecule -1	/
L max	Carrying capacity of latently infected cells	100 cells ml -1	[31]
d L	Death rate of latently infected T cells	0.001 day -1	[30]