Table 2. Mean pain (NRS) scores at baseline, 3, 6, 12 and 24 months.

	ACS/PT patients (n = 118)
Timepoint	Mean pain (NRS) score (range)	p-value compared to baseline	Effect size d compared to baseline
Baseline	8.10 (6–10)	-	-
3 months	3.00 (1–5)	p<0.001	d = 5.3
6 months	2.76 (0–4)	p<0.001	d = 5.6
12 months	2.81 (0–5)	p<0.001	d = 5.4
24 months	3.03 (0–4)	p<0.001	d = 5.1

P-values and effect sizes d are given in comparison to baseline.ACS: Autologous conditioned serum; PT: Physiotherapy; NRS: Numeric Rating Scale.