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. 2015 Dec 28;11(12):e1005724. doi: 10.1371/journal.pgen.1005724

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© 2015 Song et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — In ovules, transcription of genes in euchromatin induces activation of nearby TEs, leading to 24-nt siRNA production. These siRNAs promote CHH methylation of TEs through the RdDM pathway. However, occupation of histone H1 in heterochromatin impedes access of GhCMT2 to heterochromatin. During the fiber development, 24-nt siRNAs in euchromatin continue to induce additional CHH methylation of TEs near the genes, which eventually represses nearby genes. In heterochromatin where transcription of HISTONE H1 is repressed, GhCMT2 could access TEs in heterochromatin to promote additional CHH methylation.