Table 1. Clinical characteristics of IS patients and controls subjects.
| Cases | |||||||
|---|---|---|---|---|---|---|---|
| Controls | Total | LAA | SAO | CE | SOE | SUE | |
| (n = 774) | (n = 712) | (n = 327) | (n = 221) | (n = 54) | (n = 52) | (n = 58) | |
| Age, years | 51.5 (16.9) | 65.2 (13.9)* | 67.4 (12.5)* | 65.7 (11.7)* | 67.35 (14.02)* | 47.4 (15.2) | 65.0 (16.2)* |
| Male, % | 54 | 65.3* | 69.1* | 61.5 | 48.1 | 73.1* | 67.2 |
| BMI, kg/m2 | 22.5 (17.7) | 23.5 (23.3) | 23.9 (18.6) | 23.6 (23.3) | 22.4 (11.9) | 22.2 (12.0) | 23.5 (14.3) |
| SBP, mmHg | 125.2 (18.4) | 145.4 (22.9)* | 148.6 (22.0)* | 148.2 (23.6)* | 139.24 (20.45)* | 127.88 (20.26) | 138.42 (19.98)* |
| DBP, mmHg | 77.5 (12.1) | 84.3 (14.7)* | 85.7 (14.6)* | 86.0 (14.6)* | 81.57 (17.14) | 77.35 (11.76) | 78.93 (12.12) |
| TC, mmol/L | 4.83 (1.25) | 4.84 (1.30) | 4.90 (1.31) | 4.85 (1.30) | 4.58 (1.24) | 4.51 (1.30) | 4.96 (1.21) |
| TG, mmol/L | 1.48 (1.0) | 1.57 (1.0) | 1.56 (0.98) | 1.64 (1.03) | 1.33 (0.91) | 1.49 (0.93) | 1.67 (1.36) |
| Glucose, mmol/L | 5.57 (2.03) | 5.90 (2.26)* | 6.14 (2.56)* | 5.61 (1.76) | 6.26 (2.38) | 5.18 (1.57) | 5.91 (2.37) |
| Cigarette smoker, % | * | * | * | * | |||
| Never | 82.4 | 70.4 | 62.4 | 76 | 85.2 | 71.2 | 79.3 |
| Former | 1.8 | 3.7 | 4.6 | 4.1 | 1.9 | 0 | 1.7 |
| Current | 15.8 | 26 | 33 | 19.9 | 13 | 28.8 | 19 |
| IHD history, % | 2.2 | 7.4* | 8.6* | 3.2 | 22.2* | 0 | 10.3* |
| Hypertension history, % | 19 | 57.3* | 66.4* | 58.4* | 51.9* | 15.4 | 44.8* |
| DM history, % | 7.1 | 20.2* | 21.4* | 19.9* | 18.5* | 5.8 | 29.3* |
| Hyperlipidemia history, % | 2.6 | 6.6* | 5.2* | 8.1* | 7.4* | 3.8 | 10.3* |
| Family history of IS, % | 0.6 | 5.6* | 3.4* | 8.6* | 9.3* | 5.8* | 3.4* |
Ischemic heart disease (IHD), diabetes mellitus (DM), age, systolic blood pressure (SBP), diastolic blood pressure (DBP), and total cholesterol (TC), triglycerides (TG), and glucose values are shown as the mean (standard deviation); body mass index (BMI) is presented as the median (range), and other values as the number of individuals (n) with percentage (n/total N) in parentheses. LAA, large artery atherosclerosis; SAO, small-artery occlusion; CE, cardioembolism; SOE, stroke of other determined etiology; SUE, stroke of undetermined etiology.
*P < 0.05 vs. control.