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Accelerated abscess formation in the kidneys of S. aureus-infected C5aR1−/− and C5aR2−/− mice. H&E stained kidney sections of (A) and (E) uninfected control mice, (B) and (F) infected wild type, (C) and (G) infected C5aR1−/−, (D) and (H) infected C5aR2−/− mice obtained at 24 h after intravenous S. aureus inoculation. Abscesses are indicated by black arrows. Bacterial clusters are indicated by red arrows. Magnification, ×10 in (A), (B), (C) and (D); ×40 in (E), (F), (G) and (H).
