| Aβ | amyloid beta peptide |
| ACC | acetyl CoA carboxylase |
| AcLDL | acetylated low-density lipoprotein |
| ACO2 | mitochondrial aconitase |
| Acr-dG | adduct of deoxyguanosine and acrolein |
| AD | Alzheimer disease |
| ADH | alcohol dehydrogenase |
| ADP-iron | adenosine diphosphate-iron |
| AICAR | 5-aminoimidazole-4-carboxyamide ribonucleoside |
| AIDS | acquired immuno-deficiency syndrome |
| AIE | approximate intracellular concentration (extinction) |
| AKR | aldo-keto reductase |
| ALD | alcoholic liver disease |
| ALDH | aldehyde dehydrogenase |
| Al-PEs | aldehyde-modified PEs |
| ALS | amyotrophic lateral sclerosis |
| AMD | age-related macular degeneration |
| AMPK | AMP-activated protein kinase |
| ANT | adenine nucleotide translocase |
| ApoB | apolipoprotein B-100 |
| AR | aldose reductase |
| ARE | antioxidant response element |
| BAG3 | Bcl-2- associated athanogene 3 |
| BER | base excision repair |
| BSA | bovine serum albumin |
| BSO | l-buthionine-S,R-sulfoximine |
| CAR | carnosine |
| CCl4 | carbon tetrachloride |
| CERAD | consortium to establish a registry for Alzheimer disease |
| CH2Cl2 | dichloromethane |
| CHO | Chinese-hamster ovary |
| CHOP | C/EBP homologous protein |
| Col II | collagen type II |
| COX-2 | cyclooxygenase-2 |
| CYP | cytochrome P450 |
| ɛ-dA | 1,N(6)-etheno-2'-deoxyadenosine |
| DHN | dihydroxynonene, non-2-ene-1,4-diol |
| DHN-MA | dihydroxynonene-mercapturic acid |
| DNA | desoxy-ribonucleic acid |
| DNA-PK | DNA-dependent protein kinase |
| DOX | doxorubicin |
| D3T | 3H-1,2-dithiole-3-thione, inducing detoxification enzymes |
| eEF-2 | Eukaryotic Elongation factor 2 |
| EGFP | enhanced green fluorescent protein |
| EGFR | epidermal growth factor receptor |
| EHN | 2,3-epoxy-4-hydroxy-nonanal |
| ERK1 | extracellular signal-regulated kinase 1 |
| ESI-MS-MS | electrospray ionization triple quadrupole mass spectrometry |
| FABP | fatty acid-binding protein |
| FAK | α1β1-integrin-focal adhesion kinase |
| FID | flame ionization detection |
| FITC | fluorescein isothiocyanate |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GC | gas chromatography |
| GC/MS | gas chromatography/mass spectrometry |
| GERD | gastroesophageal reflux disease |
| GRP78 | glucose-regulated protein 78 |
| GRX | glutaredoxin |
| GSH | glutathione |
| GSH-DHN | glutathione-dihydroxynonene conjugate |
| GSK3β | glycogen synthase kinase-3-β |
| GSSG | glutathione in the oxidized form, glutathione disulfide |
| GST | glutathione-S-transferase |
| HA-1 | Chinese hamster fibroblast control cells |
| HAEC | human aortic endothelial cell |
| Hb | hemoglobin |
| HCC | hepatocellular carcinoma |
| HCV | hepatitis C virus |
| HMEC-1 | immortalized human microvascular endothelial cells |
| HHE | 4-hydroxy-hexenal |
| [3H]HNE | tritium labeled hydroxynonenal |
| HNA | hydroxynonenoic acid |
| HNA-GSH | hydroxynonenoic acid-glutathione conjugate |
| HNE | 4-hydroxy-nonenal |
| HNE-dG | 1,N-2-propane adduct of guanine and HNE |
| HNE-H2A | HNE-modified histone-H2A |
| H2O2 | hydrogen peroxide |
| HPLC | high performance liquid chromatography |
| HPNE | 4-hydroperoxy-2-nonenal |
| HO-1 | heme oxygenase-1 |
| HSA | human serum albumin |
| HU | HU hydroxyurea |
| HUVEC | human umbilical vein endothelial cell |
| ICAM-1 | intercellular adhesion molecule-1 |
| IsoLGs | isolevuglandins |
| iTRAQ | isobaric Tags for Relative and Absolute Quantitation |
| LA | linolenic acid |
| LAD | late Alzheimer disease |
| LADH | lipoamide dehydrogenase |
| LCA | retinal dystrophy Leber congenital amaurosis |
| LC-MS/MS | liquid chromatography-tandem mass spectrometry |
| LDH | lactate dehydrogenase |
| LDL | low density lipoprotein |
| LKB1 | liver kinase B1 |
| LOX1 | lectin-like oxidized low-density lipoprotein receptor-1 |
| LPO | lipid peroxidation |
| MAL-6 | 2,2,6,6-tetramethyl-4-maleimidopiperidin-1-oxyl |
| MALDI-TOF | matrix-assisted laser desorption/ionization-time of flight |
| MAPK | mitogen-activated protein kinase |
| MBP-1 | c-myc binding protein-1 |
| MCI | mild cognitive impairment |
| MDA | malondialdehyde |
| MDM2 | mouse double minute 2 |
| MH1C1 | rat hepatoma cells |
| MMP-13 | matrix metalloproteinase 13 |
| MRP-1 | multidrug resistance protein-1 |
| NAD+ | nicotinamid dinucleotide, oxidized form |
| NADH | nicotinamid dinucleotide, reduced form |
| NADP | nicotinamid dinucleotide phosphate |
| NAFLD | non-alcoholic fatty liver disease |
| NEP | neprilysin |
| NER | nucleotide excision repair |
| Nrf2 | NF-E2-related factor 2 |
| OA | osteoarthritic |
| OC5 and OC14 | Chinese hamster fibroblast H2O2-resistant cell lines |
| ONE | 4-oxo-nonenal |
| oxLDL | oxidized low-density lipoprotein |
| ox-PAPC | oxidized PAPC |
| PAF | 1-O-alkyl-2-acetyl-sn-glycero-3-phospho-choline |
| PAPC | 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phospho-choline |
| PCAD | preclinical Alzheimer disease |
| PDGF | platelet-derived growth factor |
| PDI | protein disulfide isomerase |
| PE | phosphatidyl-ethanolamine |
| PGE | prostaglandin E |
| Pin1 | peptidyl-prolyl cis/trans-isomerase A1 |
| PMF | peptide mass fingerprinting |
| POS | photoreceptor outer segment |
| PG(E2) | prostaglandin E2 |
| PtdIns(3,4,5)P-3 | phosphatidylinositol-3,4,5-trisphosphate |
| PTEN | phosphatase and tensin homolog deleted on chromosome 10 |
| RAS | rennin/angiotensin system |
| RBC | erythrocytes |
| RDH | retinol dehydrogenase |
| RLIP76 | Ral-binding GTPase activating protein |
| ROC | receiver operator curves |
| ROOH | lipid hydroperoxide |
| ROS | reactive oxygen species |
| RPE | retinal pigment epithelial |
| SAM | sterile-alpha motif |
| SCFAs | short chain fatty acids |
| SERCA1a | serco/endoplasmic reticulum Ca2+-ATPase |
| SIRT3 | sirtuin 3 |
| SLE | systemic lupus erythematosus |
| SMC | smooth muscle cell |
| sXBP1 | spliced X-box-binding protein-1 |
| α-Syn | α-synuclein |
| TBA-RS | thiobarbituric acid-reactive substances |
| TBI | traumatic brain injury |
| TLC | thin layer chromatography |
| TLR | toll-like receptor |
| TRPV1 | transient receptor potential vanilloid 1 |
| TRX | thioredoxin |
| TrxR | thioredoxin reductase |
| UCP | uncoupling protein |
| UPR | unfolded protein response |
| VSL#3 | a medical food delivering high amount of beneficial live bacteria |
| YAP1 | Yeast Activator Protein 1 |
| ZAK kinase | sterile alpha motif and leucine zipper containing kinase (AZK) |