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. 2015 Oct 16;5(4):2659–2674. doi: 10.3390/biom5042659

Figure 1.

Figure 1

3-MA promotes but rapamycin prevents chronic ethanol induced liver injury in WT and KI mice. WT, KO and KI mice were fed with a Lieber-DeCarli liquid diet for four weeks. In the last week some mice were received an IP injection of saline, 3-MA or rapamycin once a day for seven days. ALT (A) and AST transaminase activities (B) and levels of triglyceride (TG) (C) were determined in the serum. &, p < 0.05 compared with Dextrose control, n = 4; *, p < 0.05 compared with alcohol alone-treated mice, N = 4.