Skip to main content
. 2015 Oct 16;5(4):2659–2674. doi: 10.3390/biom5042659

Figure 3.

Figure 3

3-MA enhances while rapamycin blunts oxidative stress in chronic alcohol-fed WT and KI mice. GSH levels (A) in WT, KO and KI mice. 3-MA potentiates the decline in GSH produced by ethanol whereas rapamycin prevents this decrease of GSH in WT and KI mice; TBARS (B) are elevated by ethanol feeding in WT and KI but not in KO mice. 3-MA enhances ethanol induced TBARS but rapamycin lowers this increase. &, p < 0.05 compared with dextrose control; *, p < 0.05 compared with chronic alcohol alone, N = 4.