Table 1.
Summary of patient demographic characteristics (PK population, n = 601)
Covariate | |
---|---|
Gender, women [n (%)] | 183 (30) |
Age (years) | 71 [34–93] |
Body weight (kg) | 85 [47–167] |
CLcr (ml min−1) | 76 [28–187] |
eGFR (ml min−1) | 70 [20–135] |
Results are presented as absolute numbers (%) or as the median [range]. The patients included in the PK/PD modelling of fibrin D‐dimer effect (n = 265), had similar patient characteristics. CLcr, creatinine clearance calculated using the Cockroft–Gault equation 18; eGFR, estimated glomerular filtration rate calculated using the MDRD equation 17.