Table 2.

Estimated effects of the change in Medicines and Healthcare Products Regulatory Agency guidance in the management of paracetamol poisoning. Data shown are model‐calculated numbers for admissions without the change (first column) as opposed to the predicted effect of the change (second column) with 95% confidence intervals (CIs) in September 2013, 12 months after the guideline change. The proportion of child admissions is significantly greater post‐change (Chi‐square 32.486, P < 0.001)

	Estimated admissions for September 2013
	Without guideline change	With guideline change	Absolute effect (95% CI)	Relative effect (95% CI)
All	3727	4270	543 (243, 843)	14.6 % (6.0, 23.0)
Adult	3418	3844	426 (148, 704)	12.5 % (4.5, 19.9)
Child	310	425	116 (63, 169)	37.3 % (17.2, 67.4)