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. 2015 Oct 26;80(6):1315–1323. doi: 10.1111/bcp.12755

Table 2.

Enzyme inhibitors by second, third and fourth generation for 2013 only (1.3%)

Enzyme inhibitors Number of claims 2013 Second Third Fourth Other (patch, etc.)
Valproic acid 1294 429 (33.2%) 381 (29.4%) 473 (36.6%) 11 (0.8%)
Diazepam + other benzodiazepines 6044 1481 (24.5%) 1607 (26.6%) 2278 (37.7%) 678 (11.2%)
Atrovastatin 1144 249 (21.8%) 365 (31.9) 496 (43.4%) 34 (3.0%)
Rosuvastatin 990 158 (16.0%) 293 (29.6%) 508 (51.3%) 31 (3.1%)
Verapamil 54 16 (29.6%) 27 (50%) 5 (9.3%) 6 (11.1%)
Diltiazam 38 11 (28.9%) 12 (31.6%) 15 (39.5%)
Etorcoxib 633 200 (31.6%) 172 (27.2%) 215 (34.0%) 46 (7.3%)
Cimetidine 23 0 9 (39.1%) 14 (60.9%)
Fluconazole 1556 506 (32.5%) 287 (18.4%) 622 (40.0%) 141 (9.1%)