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. 2015 Nov 17;96(5):338–349. doi: 10.1111/iep.12144

Figure 1.

Figure 1

Chronological schedule for the experimental design in days. (a) At 90 days of age, five (5) rats per dose level (1.87, 3.75, 7.5, and 15 mg/kg) were assigned to the end of the dosing period (15 days) and euthanized. (b) Five (5) rats per dose level (1.87, 3.75, 7.5 and 15 mg/kg) received the respective treatment for 15 days and were maintained without further treatment into the 30‐day recovery period followed by euthanasia. (c) Five (5) rats per dose level (1.87, 3.75, 7.5, and 15 mg/kg) received the respective treatment for 15 days and were maintained without further treatment into the 60‐day recovery period followed by euthanasia.