N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine‐induced rat bladder lesions. (a) Control animal. Normal bladder urothelium (100×). (b) Nodular hyperplasia (nh, 40×). (c) Urothelial dysplasia (d, 400×). (d) Squamous metaplasia (sqm, 200×). (e) Urothelial papilloma (pap, 100×). (f) Papillary tumour of low malignant potential (ptlmp, 100×). (g) Low‐grade urothelial carcinoma (lgpc, 40×). h, high‐grade papillary carcinoma (hgpc, 400×).