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. 2015 Dec 1;81(1):101–112. doi: 10.1111/bcp.12781

Figure 1.

Figure 1

Pharmacokinetic model for intrathecal baclofen, based on the diffusion–distribution model from Shafer & Shafer 8. The intrathecal space (V1) is distributed in a series of 57 connected compartments. Each compartment communicates with the adjacent tissue (V2). The caudal end of the model is closed, the rostral end is open