Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 6;2(12):1085–1104. doi: 10.1002/acn3.261

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published 2015. This article is a U.S. Government work and is in the public domain in the USA. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Loss of hippocampal interneurons during early development of Cln1 ^−/− mice. Representative images of hippocampal sections from WT mice (upper panels) and those from their Cln1 ^−/− littermates (lower panels) stained for GABAergic interneuron markers at 1 month (A and C) and 6 months of age (B and D). Markers examined were CCK, CoupTFII, SOM, and PV. Pooled group data for cell density counts of the labeled interneurons in WT and Cln1 ^−/− are provided in (C) and (D) for mice aged 1 and 6 months, respectively; (C) a total of 24 sections per marker from 3 different WT and Cln1 ^−/− mice were processed and counted parallel; (D) a total of 8–12 sections per marker from a WT mouse and those from a Cln1 ^−/− littermate were examined. Excel student t‐test was used for statistical analysis of the data, P < 0.01. WT, wild‐type; CCK, cholecystokinin; CoupTFII, COUP transcription factor 2; SOM, somatostatin; PV, parvalbumin.