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. 2015 Nov 9;2(12):1105–1115. doi: 10.1002/acn3.262

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Published 2015. This article is a U.S. Government work and is in the public domain in the USA. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Reduction in blood–brain barrier breakdown and of macrophages in animals treated with deep hypothermia. (A and B) These images show IgG‐like immunoreactivity in the frontoparietal cortex 48 h following status epilepticus in a normothermic (A) and hypothermic (B) animal. Bars = 100 microns. (C–F) These images show staining with a macrophage marker in frontoparietal cortex (C and D), hippocampus (E) and piriform cortex (F) of normothermic (C, E, and F) and hypothermic animals (D). Bars = 100 microns.