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. Author manuscript; available in PMC: 2015 Dec 29.
Published in final edited form as: Dis Mon. 2013 Apr;59(4):119–138. doi: 10.1016/j.disamonth.2013.01.003

Fig. 2.

Fig. 2

Mechanisms of aminoglycoside-induced outer hair cell damage. AG, aminoglycoside; AG–Fe, aminoglycoside– iron complex; ROS, reactive oxygen species; JNK, c-Jun N-terminal kinase; Cyt C, cytochrome C. Adapted from Rybak and Ramkumar.21