TABLE II.

Differential Diagnosis of Precocious Puberty

Central precocious puberty (gonadotropin-dependent)	Peripheral precocious puberty (gonadotropin-independent)
Idiopathic	Exogenous steroids
CNS tumors	Hormone-secreting tumor (hCG, adrenal androgens/cortisol, gonadal testosterone/estradiol)
Anatomic or developmental abnormality (congenital or acquired)	Genetic abnormalities
Arachnoid cyst	Mutation of LH receptor
Hydrocephalus	McCune Albright syndrome
Hamartoma	Defects in adrenal steroid biosynthesis
CNS injuries
Posttraumatic	Leydig-cell hyperplasia
Postinfectious
Posthemorrhagic	Ovarian follicle cyst
Postradiation

CNS, central nervous system; hCG, human chorionic gonadotropin; LH, luteinizing hormone.