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. 2015 Dec 2;147(1):114–124. doi: 10.1111/imm.12545

Figure 4.

Figure 4

Effect of anti‐interleukin‐22 (IL‐22) treatment or IL‐17 deficiency on colonic (a, c) chemokine and (b, d, e) inflammatory cytokine expression during Clostridium difficile colitis. Colonic gene expression was assessed via quantitative PCR as outlined in the Materials and methods. n ≥ 6 per group. Data are shown as mean ± SEM fold change gene expression of wild‐type (WT) C. difficile‐infected (black bars), C. difficile‐infected and anti‐IL‐22‐treated (grey bars), and IL‐17KO C. difficile‐infected (white bars) animals compared with untreated WT mice. CDI = C. difficile infected. *P < 0·05 compared with untreated WT animals. Brackets indicate P < 0·05 for the differences in expression levels between indicated groups.