Figure 1.

CD1d amino acid sequence alignment of different species. (a) Cotton rat CD1d (Sigmodon hispidus: KM_267558) was compared to Chinese hamster (Cricetulus griseus, GenBank: XM_007644702.1), rat (GenBank: KM_267558), mouse (GenBank: NM_007639.3), and human CD1d (GenBank: NM_001766.3). The alignment was calculated with clustal omega. Dots indicate identical amino acids, dashes indicate gaps, and asterisks indicate stop codons. The different regions are depicted in this order: signal peptide, extracellular regions α1, α2, α3 and transmembrane/intracellular regions. (b) Identical nucleotides or amino acids were counted and the overall identity was calculated as the ratio of identical nucleotides/amino acids to the length of the alignment, therefore including gaps, and are given in rounded percentages.