FIG 5.

Absence of Prdx6 does not alter bacterial burden during Y. pestis respiratory infection. Bacterial burden within lungs (A) and spleens (B) of C57BL/6 or C57BL/6 prdx6^−/− mice infected via the i.n. route with 10⁴ CFU of Y. pestis or Y. pestis Δpla after 48 h. Each point represents the number of bacteria recovered from a single mouse. The median CFU is denoted by a solid line, and the dashed line indicates the limit of detection. Data are combined from two independent experiments (n = 10 for each group; ns, not significant by Mann-Whitney U test). WT, wild type.